ABSTRACT
Objective To investigate the feasibility of inserting and detaining nasointestinal feeding tube in small bowl guided by bedside ultrasound(US)in critically ill elderly patients.Methods This was a retrospective study.Sixty four aged patients(≥ 60 years)in general ICU,the Second Affiliated Hospital of Jiaxing College,received the US-guided nasointestinal feeding tubes inserting and detaining.Feeding tubes passed through nasal and went into the stomach by manual blind method.Under US-guiding condition,the tube passed through the pyloric sphincter and further into the duodenum or jejunum.Finally the correct position of the tube head was assessed by bedside X-ray examination.Results The US-guided nasointestinal feeding tube-detaining technique was successfully operated in 57 patients(89.1％).The feeding tube heads were in the duodenum in thirty four cases(53.1 ％),and in proximal jejunum in twenty-three cases(35.9％).The untoward reaction included the bleeding of nasal cavity in 1 case,and hypotension in another case.Conclusions Bedside US-guided nasointestinal feeding tube placement is safe and feasible in aged critical patients.
ABSTRACT
Objective To investigate the feasibility of inserting and detaining nasointestinal feeding tube in small bowl guided by bedside ultrasound(US)in critically ill elderly patients.Methods This was a retrospective study.Sixty four aged patients(≥ 60 years)in general ICU,the Second Affiliated Hospital of Jiaxing College,received the US-guided nasointestinal feeding tubes inserting and detaining.Feeding tubes passed through nasal and went into the stomach by manual blind method.Under US-guiding condition,the tube passed through the pyloric sphincter and further into the duodenum or jejunum.Finally the correct position of the tube head was assessed by bedside X-ray examination.Results The US-guided nasointestinal feeding tube-detaining technique was successfully operated in 57 patients(89.1％).The feeding tube heads were in the duodenum in thirty four cases(53.1 ％),and in proximal jejunum in twenty-three cases(35.9％).The untoward reaction included the bleeding of nasal cavity in 1 case,and hypotension in another case.Conclusions Bedside US-guided nasointestinal feeding tube placement is safe and feasible in aged critical patients.
ABSTRACT
Objective: To investigate the effect of focused ultrasound on murine cervical intraepithelial neoplasia (CIN) and its possible mechanism. Methods: The mice bearing grade I CIN were orthotopically induced by dimethl benz anthracene and randomly divided into treatment group (n = 20) and control group (n = 20). The mice in the treatment group were treated with focused ultrasound, while the mice in the control group were treated with the same method but without power output. After two weeks, the pathological changes and the expressions of p16, Ki67, FasL and Fas in murine cervical tissues were detected by HE staining and immunohistochemistry, respectively. Results: The model of grade I CIN in mice was successfully established. In the treatment group, the cervical tissues returned to normal in 15 mice after treatment, 4 mice remained grade I CIN, and 1 mouse died. The response rate of treatment group was 75% (15/20). In the control group, the cervical tissues remained grade I CIN in 11 mice after treatment, 6 mice developed to grade II CIN, 1 mouse developed to grade III CIN, and 2 mice died. The response rate of the control group was 0% (0/20). There was a significant difference between the treatment group and the control group (P < 0.01). The strong positive expression rates of p16, Ki67 and FasL in cervical tissues in the treatment group were lower than those in the control group, while the strong positive expression rate of Fas was opposite (all P < 0.01). Conclusion: The focused ultrasound can effectively treat the grade I CIN in mice. This effect may be related to the changes of p16, Ki67, Fas and FasL expressions.